hrp0082p1-d2-117 | Fat Metabolism & Obesity (1) | ESPE2014

Ratio of Triglycerides to High-Density Lipoprotein Cholesterol Compared with Homeostasis Model Assessment Insulin Resistance Indexes in Screening the Metabolic Syndrome in Chinese Obese Children

Liang Jianfeng , Fu Junfen , Wang Jinling , Jiang Youjun , Dong Guanping

Background: IDF-2007 MS definition (MS-IDF2007) for children and adolescents has been challenged frequently in clinical practice and should be improved further. Therefore, it becomes imminent to explore an accessible and effective tool to screen obese children with the metabolic syndrome components.Objective and hypotheses: To investigate the optimal cut-off values and compare the accuracy for the triglycerides and HDL cholesterol ratio and homeostasis m...

hrp0082p2-d1-258 | Adrenals & HP Axis | ESPE2014

ACTH and Cortisol Levels are Associated with Cardiovascular Risk in Pediatric Obesity: a Cross-Sectional Study in China

Liang Jianfeng , Fu Junfen , Wang Jinling , Jiang Youjun , Dong Guanping

Background: The hypothalamic–pituitary–adrenal (HPA) axis, and cortisol in particular, has been reported to be involved in obesity-associated metabolic disturbances in adults and in specific populations of adolescents.Objective and hypotheses: To investigate the associations between serum ACTH and cortisol levels and cardiovascular risk factors in obese children and adolescents.Method: Of 1119 obese children and adolescen...